Primary Immunodeficiency Diseases in Adults
Dear Colleagues,
Primary immunodeficiency disorders (PIDs) are a realm where the intricacies of the immune system and the challenges faced by individuals with compromised immunity converge. This book comprehensively explores these disorders’ complexities, focusing specifically on their manifestations and management in the adult population.
PIDs are a group of rare, often genetic, conditions that leave individuals susceptible to recurrent and severe infections. While the field has made remarkable strides in understanding the genetic and molecular basis of these disorders, there is a growing need for a consolidated resource tailored to the unique considerations of adults affected by these conditions.
In this book, we bring together a group of experts to provide a holistic overview of PIDs in adults. This book of chapters in delve into the genetic underpinnings, clinical presentations, diagnostic approaches, and therapeutic interventions that characterize these disorders in the adult context.
We embark on this journey with the understanding that primary immunodeficiency disorders can significantly impact the quality of life for affected individuals. We aim to equip healthcare professionals, researchers, and students with a nuanced understanding of these disorders, fostering improved diagnosis, management, and ultimately, the well-being of those living with primary immunodeficiencies.
The content within these book is organized to serve as a valuable resource for healthcare practitioners seeking to enhance their knowledge and skills in managing adult patients with PIDs. Additionally, we hope this book will stimulate further research, collaboration, and innovation in the field, ultimately advancing our ability to provide effective and personalized care.
I would like to express my gratitude to the contributing authors for their expertise and dedication to advancing the understanding of PIDs. I also extend my appreciation to the readers for their interest in this critical area of medicine.
May this book serve as a guide, a reference, and an inspiration for all those committed to improving the lives of adults facing the challenges of PIDs.
Assoc. Prof. Dr. Fatih ÇÖLKESEN
Editor
Necmettin Erbakan University Faculty of Medicine, Department of Internal Medicine, Division of Immunology and Allergy Diseases, Konya, Türkiye
Bölümler
General Approach and Clinical Management for Adults with Primary Immunodeficiency Diseases
Mustafa İlker İNAN, Özgür KARTAL
İnan Mİ, Kartal Ö. General approach and clinical management for adults with primary immunodeficiency diseases. Çölkesen F, ed. Primary Immunodeficiency Diseases in Adults. 1st ed. Ankara: Türkiye Klinikleri; 2024. p.1-9.
Agammaglobulinemia
Yasemin AKGÜL BALABAN, Sait YEŞİLLİK
Akgül Balaban Y, Yeşillik S. Agammaglobulinemia. Çölkesen F, ed. Primary Immunodeficiency Diseases in Adults. 1st ed. Ankara: Türkiye Klinikleri; 2024. p.10-5.
Common Variable Immunodeficiency
Eray YILDIZ
Yıldız E. Common variable immunodeficiency. Çölkesen F, ed. Primary Immunodeficiency Diseases in Adults. 1st ed. Ankara: Türkiye Klinikleri; 2024. p.16-27.
IgG Subclass Deficiency
Neyran ŞERBETÇİ, Şengül BEYAZ
Şerbetçi N, Beyaz Ş. IgG subclass deficiency. Çölkesen F, ed. Primary Immunodeficiency Diseases in Adults. 1st ed. Ankara: Türkiye Klinikleri; 2024. p.28-32.
Selective IgA Deficiency and Selective IgM Deficiency
Türkan Zeynep FENDOĞLU, Şadan SOYYİĞİT
Fendoğlu TZ, Soyyiğit Ş. Selective IgA deficiency and selective IgM deficiency. Çölkesen F, ed. Primary Immunodeficiency Diseases in Adults. 1st ed. Ankara: Türkiye Klinikleri; 2024. p.33-7.
Spesific Antibody Deficiency
Ümmügülsüm YILMAZ, Eray YILDIZ
Yılmaz Ü, Yıldız E. Spesific antibody deficiency. Çölkesen F, ed. Primary Immunodeficiency Diseases in Adults. 1st ed. Ankara: Türkiye Klinikleri; 2024. p.38-44.
Combined Immunodeficiencies
Mehmet KILINÇ
Kılınç M. Combined immunodeficiencies. Çölkesen F, ed. Primary Immunodeficiency Diseases in Adults. 1st ed. Ankara: Türkiye Klinikleri; 2024. p.45-50.
Phagocytic Disorders
Fatma Arzu AKKUŞ, Şevket ARSLAN
Akkuş FA, Arslan Ş. Phagocytic disorders. Çölkesen F, ed. Primary Immunodeficiency Diseases in Adults. 1st ed. Ankara: Türkiye Klinikleri; 2024. p.51-7.
Hyper IgE Syndrome
Deniz EYİCE, Semra DEMİR
Eyice D, Demir S. Hyper IgE syndrome. Çölkesen F, ed. Primary Immunodeficiency Diseases in Adults. 1st ed. Ankara: Türkiye Klinikleri; 2024. p.58-66.
Chromosomal Breakage Syndromes Associated with Immunodeficiency
Reyhan GÜMÜŞBURUN, Ömür ARDENİZ
Gümüşburun R, Ardeniz Ö. Chromosomal breakage syndromes associated with immunodeficiency. Çölkesen F, ed. Primary Immunodeficiency Diseases in Adults. 1st ed. Ankara: Türkiye Klinikleri; 2024. p.67-74.
Flow Cytometry for the Diagnosis of Primary Immunodeficiency Diseases
Recep EVCEN
Evcen R. Flow cytometry for the diagnosis of primary immunodeficiency diseases. Çölkesen F, ed. Primary Immunodeficiency Diseases in Adults. 1st ed. Ankara: Türkiye Klinikleri; 2024. p.75-82.
Common Genetic Mutations in Adults with Primary Immunodeficiency Diseases
Mehmet Emin GEREK, Fatih ÇÖLKESEN
Gerek ME, Çölkesen F. Common genetic mutations in adults with primary ımmunodeficiency diseases. Çölkesen F, ed. Primary Immunodeficiency Diseases in Adults. 1st ed. Ankara: Türkiye Klinikleri; 2024. p.83-97.
Immunizations and Antibiotic Prophylaxis in Patients with Primary Immunodeficiency Diseases
Gülden PAÇACI ÇETİN, Nida ÖZTOP
Paçacı Çetin G, Öztop N. Immunizations and antibiotic prophylaxis in patients with primary immunodeficiency diseases. Çölkesen F, ed. Primary Immunodeficiency Diseases in Adults. 1st ed. Ankara: Türkiye Klinikleri; 2024. p.98-104.
IVIG/SCIG Treatment in Patients with Primary Immunodeficiency Diseases
Filiz SADİ AYKAN
Sadi Aykan F. IVIG/SCIG treatment in patients with primary immunodeficiency diseases. Çölkesen F, ed. Primary Immunodeficiency Diseases in Adults. 1st ed. Ankara: Türkiye Klinikleri; 2024. p.105-14.
Biological Therapies in Patients with Primary Immunodeficiency Diseases
Tuğba ÖNALAN, Şevket ARSLAN
Önalan T, Arslan Ş. Biological therapies in patients with primary immunodeficiency diseases. Çölkesen F, ed. Primary Immunodeficiency Diseases in Adults. 1st ed. Ankara: Türkiye Klinikleri; 2024. p.115-24.
Stem Cell Transplantation and Gene Therapy in Patients with Primary Immunodeficiency Diseases
Taha Ulutan KARS
Kars TU. Stem cell transplantation and gene therapy in patients with primary immunodeficiency diseases. Çölkesen F, ed. Primary Immunodeficiency Diseases in Adults. 1st ed. Ankara: Türkiye Klinikleri; 2024. p.125-8.