ADVANCEMENTS IN TISSUE ENGINEERING: TOWARDS PERSONALIZED MAXILLOFACIAL SOLUTIONS
Özgün Yıldırım
Health Sciences University, Gülhane Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Ankara, Türkiye
Yıldırım Ö. Advancements in Tissue Engineering: Towards Personalized Maxillofacial Solutions. Karasu HA, ed. Advanced Technologies in Oral and Maxillofacial Surgery. 1st ed. Ankara: Türkiye Klinikleri; 2025. p.7583.
ABSTRACT
The fourth industrial revolution took its place in history with the development of threedimensional (3D) printing technologies. Developments in this area have impacted oral and maxillofacial surgery applications as well as every branch of medicine. Designing and producing threedimensional objects, especially with computer support, have gained critical importance. Today, in oral and maxillofacial surgery, many custommade personalised preoperative structures are produced routinely by this new technology. The most important of these are titanium meshes, subperiosteal implants and reconstruc tion plates. When an implant is to be placed in the oral region, there may not be enough bone. Augmen tation may be required to provide sufficient bone content before dental implant placement. Titanium mesh has been used for augmentation purposes for many years. It is quite successful in vertical and horizontal bone augmentation procedures. There are, however, some disadvantages of using generic or nonpersonalised material. One of these is that the sharp and pointed edges formed when the titanium mesh is shaped may damage the soft tissue surrounding the titanium mesh and interfere with healing. Titanium meshes are quite popular especially in guided bone regeneration method and due to the advances in technology, custommade titanium meshes have been used recently to eliminate the disad vantage mentioned above. Subperiosteal implants can be offered as an alternative option in cases with advanced atrophic jawbones where augmentation is not performed due to patient request and physician preference. Subperiosteal implants has an even longer history, but the use of subperiosteal implants has been abandoned after the popularity of intraosseous implants increased. Advances in technology have enabled subperiosteal implants to be manufactured specifically for each individual. Today, personal ized subperiosteal implants can be designed on cone beam computed tomography images taken from patients and can be produced with threedimensional printing technologies. Very successful results have been reported in the literature. Finally, reconstruction plates are mentioned in this chapter. Various mandibular resections are performed in the treatment of deformities resulting from developmental dis orders in the jaws or in tumor surgeries. The adaptation of in vitro manufactured plates during surgery takes time and is challenging. In addition, their bending reduces the resistance of the material against fractures. For this reason, personalized reconstruction plates are also produced with threedimensional imaging and printing methods. In this way, the surgery time is shortened, the doctor has less difficulty and the fracture resistance of the material does not change.
Keywords: Oral and Maxillofacial Surgery; Titanium mesh; Subperiosteal implant; Reconstruction plate; Cone beam computed tomography; Threedimensional (3D) printing
Kaynak Göster
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