Atopik Dermatit

immunoloji alerji ozel 13-2 kapak

Pınar UYSALa
aAydın Adnan Menderes Üniversitesi Tıp Fakültesi, Çocuk İmmünolojisi ve Alerji Hastalıkları BD, Aydın, TÜRKİYE

Uysal P. Atopik dermatit. Çildağ S, editör. İmmünolojik ve Alerjik Deri Hastalıkları. 1. Baskı. Ankara: Türkiye Klinikleri; 2020. p.29-39.

ÖZET
Atopik dermatit (AD) kronik, kaşıntılı, eritem alanları ile kendini gösteren enflamatuar bir deri hastalığıdır. Atopik dermatit genetik yatkınlık, immün disregülasyon, epidermal bariyer fonksiyon bozukluğu ile ilişkilidir. Prevelansı son on yılda artarak %10-20 arasında değişmektedir. Atopik dermatitte kronik kaşıntı, yaygın cilt kuruluğu ve tipik yerleşimli egzamatöz cilt lezyonları önemli klinik bulgulardır. Tanı klinik olarak konur. Tedavisinde alerjen ve irritanlardan kaçınma, etkili nemlendirici kullanımı, topikal kortikosteroidler, kalsinörin inhibitörleri ve fosfodiesteraz inhibitörleri ile sistemik tedaviler önerilir. Ağır Atopik dermatit alevlenmelerinde ıslak pansuman uygulanabilir. Ağır morbitite ve mortaliteye neden olabilen cilt enfeksiyonları ile uzun dönemde görülebilen nöropsikiatrik bozukluklar ve kardiyovasküler hastalıklar en önemli komplikasyonlardır.

Anahtar Kelimeler: Atopik dermatit; çocuk; erişkin; egzama

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