B-Cell Targeted Therapies in Pediatric Rheumatology

cocukromatolojisi-5-1-2024

Gülşah KAVRUL KAYAALPa , Nuray AKTAY AYAZa

aİstanbul University İstanbul Faculty of Medicine, Department of Pediatric Rheumatology, İstanbul, Türkiye

ABSTRACT
B cells play a pivotal role in autoimmune rheumatic diseases by virtue of their contributions to antibody production, antigen presentation, and cytokine release. Consequently, therapeutic approaches targeting B cells have emerged as a promising strategy for managing autoimmune rheumatic diseases. In this article, we discuss the significance of B cells in pediatric rheumatic diseases and explore the B cell-targeted treatments employed in these conditions.
Keywords: Pediatric rheumatology; B-cell; belimumab; rituximab

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