Congenital Anomalies of the Iris

oftalmoloji-17-2-kapak-wosonayiyok

Emine ÇİNİCİa

aAtatürk University Faculty of Medicine, Department of Ophthalmology, Erzurum, Türkiye

ABSTRACT
The iris is the anterior part of the uveal layer of the eye. It protects the retina from phototoxic effects by adjusting the amount of light entering the eye. It occurs during the 5th intrauterine week when the neural crest cells on the back surface of the cornea undergo changes. While the iris stroma develops from neural crest cells, two epithelial layers consist of neuroectodermal tissue at the edge of the optic fossa. Congenital anomalies of the iris are often seen together with anomalies of other structures of the anterior segment due to their common embryological development. For example, as in Axenfeld-Rieger syndrome and Peters anomaly. The most common congenital iris anomalies are iris colobomas, aniridia and heterochromic iris.
Keywords: Congenital abnormalities; coloboma; aniridia

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