Diagnosis Methods of Metabolic Myopathies: Imaging Techniques (Ultrasonography, Elastography, Computed Tomography, Magnetic Resonance Imaging)

cocukmetabolizma-5-1-2024

Birsel ŞEN AKOVAa , Suat FİTOZb

aAnkara Bilkent City Hospital, Clinic of Pediatric Radiology, Ankara, Türkiye
bAnkara University Faculty of Medicine, Department of Pediatric Radiology, Ankara, Türkiye

ABSTRACT
Diagnostic imaging has a supportive role in characterizing the extent and nature of muscle involvement in metabolic myopathies. This review focuses on the utility of various imaging techniques, including ultrasound (US), elastography, computed tomography (CT), and magnetic resonance imaging (MRI), in diagnosis and assessment. Ultrasonography, with its advantages of real-time imaging and absence of ionizing radiation, is valuable for evaluating muscle diseases, especially in children. However, its sensitivity for detecting subtle changes is limited. Elastography provides information about the elasticity of tissues, but data about elastography in myopathies is lacking. CT, although effective in revealing fatty replacement and muscle atrophy, is hindered by radiation exposure concerns. MRI emerges as the preferred imaging modality, providing detailed soft tissue characterization and metabolic changes. Whole-body MRI holds promise for comprehensive assessment and disease monitoring. In conclusion, radiological imaging, particularly MRI, plays a crucial role in diagnosing and monitoring metabolic myopathies.
Keywords: Myopathies; diagnostic imaging; ultrasonography; magnetic resonance imaging

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