MOLAR INCISOR HYPOMINERALIZATION

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Endodontic Treatment for Molar Incisor Hypomineralization-Affected Teeth

Deniz YANIK NALBANTOĞLUa , Mehmet Baybora KAYAHANb
aSüleyman Demirel University Faculty of Dentistry, Department of Endodontics, Isparta, Türkiye
bİstanbul University-Cerrahpaşa Faculty of Dentistry, Department of Endodontics, İstanbul, Türkiye

Yanık Nalbantoğlu D, Kayahan MB. Endodontic treatment for molar incisor hypomineralization-affected teeth. In: Şen Tunç E, ed. Molar Incisor Hypomineralization. 1st ed. Ankara: Türkiye Klinikleri; 2025. p.61-5.

ABSTRACT
Molar incisor hypomineralization (MIH) is characterized by defective enamel, which is most fundamentally related to the tooth’s predisposition to caries and pulpal and periapical tissue diseases. For severely MIH-affected teeth, although extraction and molar substitution are recommended, these teeth may need to remain due to reasons including hypodontia or anchorage. Due to a deficiency of regular dentist check-ups, in these teeth, which are prone to post-eruptive enamel breakdown, pulp pathologies may be observed. Therefore, endodontic treatment requirements are frequently encountered. MIH-affected teeth demonstrate variations in root and canal morphology. Qualitative and quantitative changes such as increased nerve fibers are observed in the pulp. This may make it difficult to apply vitality tests. The mineral component of dentin is changed, and abundant bacteria are observed. Considering the necessity of maintaining these teeth in function, the endodontic treatment should be performed after obtaining detailed root and canal anatomy knowledge, considering factors such as severity, future orthodontic treatment, and parental attitude.

Keywords: Dental pulp; endodontic treatment; molar incisor hypomineralization; morphology; root canal

Referanslar

  1. Al-Batayneh OB, Abdelghani IM. Outcome of vital pulp therapy in deeply carious molars affected with molar incisor hypomineralisation (MIH) defects: a randomized clinical trial. Eur Arch Paediatr Dent. 2022;23(4):587-99. [Crossref]  [PubMed]
  2. Sen Yavuz B, Kaya R, Kodaman Dokumacigil N, Ozgur EG, Bekiroglu N, Kargul B. Clinical performance of short fiber reinforced composite and glass hybrid on hypomineralized molars: A 36-month randomized split-mouth study. J Dent. 2024;144:104919. [Crossref]  [PubMed]
  3. Pappa E, Vastardis H, Makridakis M, Zoidakis J, Vougas K, Stamatakis G, et al. Analysis of Human and Microbial Salivary Proteomes in Children Offers Insights on the Molecular Pathogenesis of Molar-Incisor Hypomineralization. Biomedicines. 2022;10(9):2061. [Crossref]  [PubMed]  [PMC]
  4. Haidar M, Raslan N. Comparative study of articaine 4% versus lidocaine 2% in the local anesthesia of permanent mandibular first molars affected by MIH: a randomized controlled trial. Eur Arch Paediatr Dent. 2023;24(5):621-30. [Crossref]  [PubMed]
  5. Wall A, Leith R. A questionnaire study on perception and clinical management of molar incisor hypomineralisation (MIH) by Irish dentists. Eur Arch Paediatr Dent. 2020;21(6):703-10. [Crossref]  [PubMed]
  6. Lygidakis NA, Garot E, Somani C, Taylor GD, Rouas P, Wong FSL. Best clinical practice guidance for clinicians dealing with children presenting with molar-incisor-hypomineralisation (MIH): an updated European Academy of Paediatric Dentistry policy document. Eur Arch Paediatr Dent. 2022;23(1):3-21. [Crossref]  [PubMed]  [PMC]
  7. Casagrande L, Seminario AT, Correa MB, Werle SB, Maltz M, Demarco FF, Araujo FB. Longevity and associated risk factors in adhesive restorations of young permanent teeth after complete and selective caries removal: a retrospective study. Clin Oral Investig. 2017;21(3):847-55. [Crossref]  [PubMed]
  8. Ide M, Oshima Y, Chiba T, Adaniya A, Kuroki T, Miake Y, et al. Histological findings of regional odontodysplasia in maxillary right region in two cases. Pediatric Dental Journal. 2023;33(1):7-13. [Crossref]
  9. Neboda C, Anthonappa RP, Engineer D, King NM, Abbott PV. Root canal morphology of hypomineralised first permanent molars using micro-CT. Eur Arch Paediatr Dent. 2020;21(2):229-40. [Crossref]  [PubMed]
  10. American Academy of Pediatric Dentistry. Molar-Incisor Hypomineralization, the Reference Manual of Pediatric Dentistry. American Academy of Pediatric Dentistry; 2024. p.444-51.
  11. Altan H, Yilmaz RE. Clinical evaluation of resin infiltration treatment masking effect on hypomineralised enamel surfaces. BMC Oral Health. 2023;23(1):444. [Crossref]  [PubMed]  [PMC]
  12. Yanık D, Kuştarcı A. Kök ve Kök Kanal Morfolojisinde Simetri. Turkiye Klinikleri Endodontics-Special Topics. 2023;9(2):127-33.
  13. Neboda C, Anthonappa RP, King NM. Preliminary investigation of the variations in root canal morphology of hypomineralised second primary molars. Int J Paediatr Dent. 2018;28(3):310-8. [Crossref]  [PubMed]
  14. Özükoç C. Examination of root canal morphology of teeth affected by Molar Incisor Hypomineralization (MIH): Frequency of accessory canals. International Dental Research. 2021;11(1):12-5. [Crossref]
  15. Wolf TG, Paqué F, Woop AC, Willershausen B, Briseño-Marroquín B. Root canal morphology and configuration of 123 maxillary second molars by means of micro-CT. Int J Oral Sci. 2017;9(1):33-7. [Crossref]  [PubMed]  [PMC]
  16. Eaton JA, Clement DJ, Lloyd A, Marchesan MA. Micro-Computed Tomographic Evaluation of the Influence of Root Canal System Landmarks on Access Outline Forms and Canal Curvatures in Mandibular Molars. J Endod. 2015;41(11):1888-91. [Crossref]  [PubMed]
  17. Heijs SC, Dietz W, Norén JG, Blanksma NG, Jälevik B. Morphology and chemical composition of dentin in permanent first molars with the diagnose MIH. Swed Dent J. 2007;31(4):155-64.
  18. Dhote VS, Padawe DS, Takate VS, Dighe KS, Tanna M, Dharmadhikari PM. Molar incisor hypomineralisation and bilateral radix entomolaris in mandibular first permanent molars: a rare case report and literature review. Baba Farid University Dental Journal. 2018;8(1):68-76.
  19. Walshaw EG, Noble F, Conville R, Anne Lawson J, Hasmun N, Rodd H. Molar incisor hypomineralisation and dental anomalies: A random or real association? Int J Paediatr Dent. 2020;30(3):342-8. [Crossref]  [PubMed]
  20. Şen Yavuz B, Sezer B, Kaya R, Tuğcu N, Kargül B. Is there an association between molar incisor hypomineralization and developmental dental anomalies? A case-control study. BMC Oral Health. 2023;23(1):776. [Crossref]  [PubMed]  [PMC]
  21. Hargreaves KM, Goodis HE, Tay FR. Seltzer and Bender's dental pulp. Batavia, IL, USA: Quintessence Pub.; 2012.
  22. Fu X, Kim HS. Dentin Mechanobiology: Bridging the Gap between Architecture and Function. Int J Mol Sci. 2024;25(11):5642. [Crossref]  [PubMed]  [PMC]
  23. Foster BL, Chu EY, Hujoel PP. Vitamin D in dentoalveolar and oral health. Feldman and Pike's Vitamin D. 2024. p.453-84. [Crossref]
  24. D'Ortenzio L, Kahlon B, Peacock T, Salahuddin H, Brickley M. The rachitic tooth: Refining the use of interglobular dentine in diagnosing vitamin D deficiency. Int J Paleopathol. 2018;22:101-8. [Crossref]  [PubMed]
  25. Okawa R, Hamada M, Takagi M, Matayoshi S, Nakano K. A Case of X-Linked Hypophosphatemic Rickets with Dentin Dysplasia in Mandibular Third Molars. Children (Basel). 2022;9(9):1304. [Crossref]  [PubMed]  [PMC]
  26. Kagayama M, Zhu J, Sasano Y, Sato H, Mayanagi H. Development of interglobular dentine in rat molars and its relation to maturation of enamel. Anat Embryol 1997;196:477-83. [Crossref]  [PubMed]
  27. Feltrin-Souza J, Fonseca-Souza G, Pinheiro E, Fraiz FC, Cerri PS. Systemic and Environmental Risk Factors Associated with Molar Incisor Hypomineralisation. Monogr Oral Sci. 2024;32:117-139. [Crossref]  [PubMed]
  28. Trévia LRA, de Castro VA, Valadas LAR, Tapety CMC, de Sousa Pereira M, Chagas FO, et al. Molar Incisor Hypomineralization (MIH): Literature Review and Case Report. J Young Pharm. 2020;12(2):182-4. [Crossref]
  29. Peled Y, Stewart CA, Glogauer M, Finer Y. The Role of Bacterial, Dentinal, Salivary, and Neutrophil Degradative Activity in Caries Pathogenesis. Dent J (Basel). 2023;11(9):217. [Crossref]  [PubMed]  [PMC]
  30. Özgül BM, Sakaryalı D, Tirali RE, Çehreli SB. Does MIH Affects Preoperative and Intraoperative Hypersensitivity? J Clin Pediatr Dent. 2022;46(3):204-10. [Crossref]  [PubMed]
  31. Rodd HD, Boissonade FM, Day PF. Pulpal status of hypomineralized permanent molars. Pediatr Dent. 2007;29(6):514-20.
  32. Rodd HD, Boissonade FM. Substance P expression in human tooth pulp in relation to caries and pain experience. Eur J Oral Sci. 2000;108(6):467-74. [Crossref]  [PubMed]
  33. Hargreaves KM, Cohen S. Cohen's pathways of the pulp. 10th ed. St. Louis: Mosby Inc; 2010.
  34. Aykanat B, Elbay M. Effect of photobiomodulation on the efficacy of anesthesia in maxillary permanent molar teeth with molar incisor hypomineralization: A randomized clinical trial. Int J Paediatr Dent. 2024;34(3):219-28. [Crossref]  [PubMed]
  35. Afzal SH, Skaare AB, Wigen TI, Brusevold IJ. Molar-Incisor Hypomineralisation: Severity, caries and hypersensitivity. J Dent. 2024;142:104881. [Crossref]  [PubMed]
  36. Taylor GD, Vernazza CR, Abdulmohsen B. Success of endodontic management of compromised first permanent molars in children: a systematic review. Int J Paediatr Dent. 2020;30(3):370-80. [Crossref]  [PubMed]
  37. Çağırır Dindaroğlu F, Özay Güngör N. Comparison of the vitality test with sensitivity tests in mature and immature teeth: clinical trial. BMC Oral Health. 2024;24(1):613. [Crossref]  [PubMed]  [PMC]
  38. Wolters WJ, Duncan HF, Tomson PL, Karim IE, McKenna G, Dorri M, et al. Minimally invasive endodontics: a new diagnostic system for assessing pulpitis and subsequent treatment needs. Int Endod J. 2017;50(9):8259. [Crossref]  [PubMed]
  39. Elhennawy K, Jost-Brinkmann PG, Manton DJ, Paris S, Schwendicke F. Managing molars with severe molar-incisor hypomineralization: A cost-effectiveness analysis within German healthcare. J Dent. 2017;63:65-71. [Crossref]  [PubMed]
  40. da Costa Rosa T, Spinelli LR, da Silva FMF, de Castro Costa M, de Almeida Neves A. Perceptions, attitudes, and clinical experiences of Brazilian dental practitioners towards molar incisor hypomineralisation: a cross-sectional study. Eur Arch Paediatr Dent. 2024;25(6):855-68. [Crossref]  [PubMed]
  41. Osborne R, Silva M, Taylor GD. Qualitative study exploring general dental practitioners' views of MIH and its management in the UK and Australia. Int J Paediatr Dent. 2024;34(4):372-82. [Crossref]  [PubMed]
  42. Murray JJ, Vernazza CR, Holmes RD. Forty years of National Survey: an overview of children's dental health from 1973 to 2013. Br Dent J. 2015;219(6):281-5. [Crossref]  [PubMed]