HEALTHY EATING DURING PREGNANCY

Berivan Güzelbağ

Sultangazi Haseki Training and Research Hospital,Department of Gynecology and Obstetrics ,İstanbul, Türkiye

Güzelbağ B. Healthy Eating During Pregnancy. Çetin A, ed. A Guide to Healthy Pregnancy: Managing Ailments and Finding Solutions. 1st ed. Ankara: Türkiye Klinikleri; 2025. p.157-168.

ABSTRACT

Healthy eating during pregnancy is crucial for both maternal and fetal health, directly influencing immediate pregnancy outcomes and the child’s long-term well-being. Adequate and balanced nutrition plays a pivotal role in supporting fetal organ development, ensuring maternal health, and mitigating the risk of chronic conditions in offspring, aligning with the principles of fetal programming. Nutritional inadequacies, including insufficient intake of folic acid, iron, and calcium, have been linked to adverse outcomes such as gestational diabetes, preeclampsia, and neural tube defects.

Macronutrient balance is of significant importance during pregnancy. Protein intake is vital for promoting fetal growth and facilitating maternal tissue repair, with increasing demands in the second and third trimesters. Carbohydrate consumption supports energy requirements and stabilizes blood glucose levels, emphasizing the inclusion of complex carbohydrates and dietary fiber to lower the risk of gestational diabetes. Healthy fats, particularly omega-3 fatty acids, are essential for fetal brain and retinal development. Seafood, when carefully selected to minimize mercury exposure, serves as a recommended source. Additionally, plant-based fats, including flaxseed and walnuts, can provide an alternative for individuals with specific dietary restrictions.

Micronutrients are equally vital, with folic acid intake reducing neural tube defects by 70%. Iron supports increased blood volume and oxygen transport, with daily supplementation often necessary to prevent anemia. Calcium aids fetal skeletal development, while vitamin D supports bone health and immune function. Iodine is critical for thyroid hormone synthesis, and deficiencies can lead to developmental delays. Other essential nutrients include choline, zinc, and vitamin B12, with tailored supplementation addressing specific dietary gaps.

Weight management is another cornerstone of prenatal care. Appropriate weight gain, guided by pre-pregnancy BMI, supports healthy fetal growth while minimizing risks like gestational diabetes, preeclampsia, and postpartum obesity. Monitoring weight gain at regular intervals ensures early intervention for potential complications. Excessive weight gain, particularly in overweight individuals, may increase the risk of delivery complications and postpartum obesity.

Special circumstances, such as gestational diabetes or multiple pregnancies, require customized dietary strategies. Vegan or vegetarian diets during pregnancy can meet nutritional needs with careful planning, focusing on plant-based proteins, fortified foods, and omega-3 supplementation. Cultural and socioeconomic factors also influence dietary patterns, necessitating adaptable recommendations that respect traditional practices while promoting health. Providing affordable, nutrient-dense options and utilizing food assistance programs can bridge gaps for economically disadvantaged families.

Pregnancy presents a unique opportunity to enhance maternal and fetal health through informed nutritional strategies. Regular monitoring and individualized dietary counseling from healthcare professionals are essential to optimize outcomes, ensuring a healthy pregnancy and lifelong well-being for both mother and child.

Keywords: Pregnancy; Maternal health; Diet; Food and nutrition; Dietary supplements

Referanslar

  1. Fowles ER, Fowles SL. Healthy eating during pregnancy: determinants and supportive strategies. J Community Health Nurs. 2008;25(3):138-152. [Crossref]  [PubMed]
  2. American College of Obstetricians and Gynecologists. ACOG Committee opinion no. 548: weight gain during pregnancy. Obstet Gynecol. 2013;121(1):210-212. [Crossref]  [PubMed]
  3. Koletzko B, Cremer M, Flothkötter M, et al. Diet and Lifestyle Before and During Pregnancy - Practical Recommendations of the Germany-wide Healthy Start - Young Family Network. Geburtshilfe Frauenheilkd. 2018;78(12):1262-1282. [Crossref]  [PubMed]  [PMC]
  4. Robb L, Joubert G, Walsh CM. Diet quality indexes for use during pregnancy: a scoping review. Nutr Rev. 2024;82(11):1622-1630. [Crossref]  [PubMed]  [PMC]
  5. Snetselaar LG, de Jesus JM, DeSilva DM, Stoody EE. Dietary Guidelines for Americans, 2020-2025: Understanding the Scientific Process, Guidelines, and Key Recommendations. Nutr Today. 2021;56(6):287-295. [Crossref]  [PubMed]  [PMC]
  6. Mousa A, Naqash A, Lim S. Macronutrient and Micronutrient Intake during Pregnancy: An Overview of Recent Evidence. Nutrients. 2019;11(2):443. Published 2019 Feb 20. [Crossref]  [PubMed]  [PMC]
  7. Blumfield ML, Collins CE. High-protein diets during pregnancy: healthful or harmful for offspring?. Am J Clin Nutr. 2014;100(4):993-995. [Crossref]  [PubMed]
  8. Procter SB, Campbell CG. Position of the Academy of Nutrition and Dietetics: nutrition and lifestyle for a healthy pregnancy outcome. J Acad Nutr Diet. 2014;114(7):1099-1103. [Crossref]  [PubMed]
  9. Qiu C, Coughlin KB, Frederick IO, Sorensen TK, Williams MA. Dietary fiber intake in early pregnancy and risk of subsequent preeclampsia [published correction appears in Am J Hypertens. 2008 Oct;21(10):1169]. Am J Hypertens.2008;21(8):903-909. [Crossref]  [PubMed]
  10. Middleton P, Gomersall JC, Gould JF, Shepherd E, Olsen SF, Makrides M. Omega-3 fatty acid addition during pregnancy. Cochrane Database Syst Rev. 2018;11(11):CD003402. Published 2018 Nov 15. [Crossref]  [PubMed]
  11. Jiang Y, Chen Y, Wei L, et al. DHA supplementation and pregnancy complications. J Transl Med. 2023;21(1):394. Published 2023 Jun 17. [Crossref]  [PubMed]  [PMC]
  12. Keats EC, Haider BA, Tam E, Bhutta ZA. Multiple-micronutrient supplementation for women during pregnancy. Cochrane Database Syst Rev. 2019;3(3):CD004905. Published2019 Mar 14. [Crossref]  [PubMed]  [PMC]
  13. Wolf HT, Hegaard HK, Huusom LD, Pinborg AB. Multivitamin use and adverse birth outcomes in high-income countries: a systematic review and meta-analysis. Am J Obstet Gynecol. 2017;217(4):404.e1-404.e30. [Crossref]  [PubMed]
  14. Vitamin supplementation in pregnancy. Drug Ther Bull.2016;54(7):81-84. [Crossref]  [PubMed]
  15. Moos MK, Dunlop AL, Jack BW, et al. Healthier women, healthier reproductive outcomes: recommendations for the routine care of all women of reproductive age. Am J Obstet Gynecol. 2008;199(6 Suppl 2):S280-S289. [Crossref]  [PubMed]
  16. Ghishan FK, Kiela PR. Vitamins and Minerals in Inflammatory Bowel Disease. Gastroenterol Clin North Am. 2017;46(4):797-808. [Crossref]  [PubMed]  [PMC]
  17. Goodnight W, Newman R; Society of Maternal-Fetal Medicine. Optimal nutrition for improved twin pregnancy outcome. Obstet Gynecol. 2009;114(5):1121-1134. [Crossref]  [PubMed]
  18. Sebastiani G, Herranz Barbero A, Borrás-Novell C, et al. The Effects of Vegetarian and Vegan Diet during Pregnancy on the Health of Mothers and Offspring. Nutrients. 2019;11(3):557. Published 2019 Mar 6. [Crossref]  [PubMed]  [PMC]
  19. Shawe J, Ceulemans D, Akhter Z, et al. Pregnancy after bariatric surgery: Consensus recommendations for periconception, antenatal and postnatal care. Obes Rev.2019;20(11):1507-1522. [Crossref]  [PubMed]  [PMC]
  20. WHO Guidelines Approved by the Guidelines Review Committee, in WHO antenatal care recommendations for a positive pregnancy experience: Nutritional interventions update: Multiple micronutrient supplements during pregnancy. World Health Organization© World Health Organization 2020; PMID: 32783435.Geneva. [Link]
  21. Viswanathan M, Urrutia RP, Hudson KN, Middleton JC, Kahwati LC. Folic Acid Supplementation to Prevent Neural Tube Defects: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA. 2023;330(5):460-466. [Crossref]  [PubMed]
  22. McNulty B, McNulty H, Marshall B, et al. Impact of continuing folic acid after the first trimester of pregnancy: findings of a randomized trial of Folic Acid Supplementation in the Second and Third Trimesters. Am J Clin Nutr.2013;98(1):92-98. [Crossref]  [PubMed]
  23. Bailey RL, Pac SG, Fulgoni VL 3rd, Reidy KC, Catalano PM. Estimation of Total Usual Dietary Intakes of Pregnant Women in the United States. JAMA Netw Open.2019;2(6):e195967. Published 2019 Jun 5. [Crossref]  [PubMed]  [PMC]
  24. McLean E, Cogswell M, Egli I, Wojdyla D, de Benoist B. Worldwide prevalence of anaemia, WHO Vitamin and Mineral Nutrition Information System, 1993-2005. Public Health Nutr. 2009;12(4):444-454. [Crossref]  [PubMed]
  25. Cantor AG, Holmes R, Bougatsos C, Atchison C, DeLoughery T, Chou R. Screening and Supplementation for Iron Deficiency and Iron Deficiency Anemia During Pregnancy: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA. 2024;332(11):914-928. [Crossref]  [PubMed]
  26. Finkelstein JL, Cuthbert A, Weeks J, et al. Daily oral iron supplementation during pregnancy. Cochrane Database Syst Rev. 2024;8(8):CD004736. Published 2024 Aug 15. [Crossref]  [PubMed]
  27. Fairweather-Tait S. How much iron does a healthy pregnant woman require?. Am J Clin Nutr. 2022;115(4):985-986. [Crossref]
  28. Recommendations to prevent and control iron deficiency in the United States. Centers for Disease Control and Prevention. MMWR Recomm Rep. 1998;47(RR-3):1-29. [PubMed]
  29. WHO Guidelines Approved by the Guidelines Review Committee, in Guideline: Daily Iron and Folic Acid Supplementation in Pregnant Women. 2012, World Health Organization Copyright© 2012, World Health Organization.: Geneva. [Link]
  30. Stoffel NU, Cercamondi CI, Brittenham G, et al. Iron absorption from oral iron supplements given on consecutive versus alternate days and as single morning doses versus twice-daily split dosing in iron-depleted women: two open-label, randomised controlled trials. Lancet Haematol. 2017;4(11):e524-e533. [Crossref]  [PubMed]
  31. Peña-Rosas JP, De-Regil LM, Gomez Malave H, Flores-Urrutia MC, Dowswell T. Intermittent oral iron supplementation during pregnancy. Cochrane Database Syst Rev.2015;2015(10):CD009997. Published 2015 Oct 19. [Crossref]
  32. Institute of Medicine (US) Panel on Micronutrients. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington (DC): National Academies Press (US); 2001. [Link]
  33. Hurrell R, Egli I. Iron bioavailability and dietary reference values. Am J Clin Nutr. 2010;91(5):1461S-1467S. [Crossref]  [PubMed]
  34. Hacker AN, Fung EB, King JC. Role of calcium during pregnancy: maternal and fetal needs. Nutr Rev. 2012;70(7):397-409. [Crossref]  [PubMed]
  35. Hofmeyr GJ, Lawrie TA, Atallah ÁN, Torloni MR. Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems. Cochrane Database Syst Rev. 2018;10(10):CD001059. Published 2018 Oct 1. [Crossref]  [PubMed]
  36. Buppasiri P, Lumbiganon P, Thinkhamrop J, Ngamjarus C, Laopaiboon M, Medley N. Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes. Cochrane Database Syst Rev.2015;2015(2):CD007079. Published 2015 Feb 25. [Crossref]  [PubMed]  [PMC]
  37. Venter C, Agostoni C, Arshad SH, et al. Dietary factors during pregnancy and atopic outcomes in childhood: A systematic review from the European Academy of Allergy and Clinical Immunology. Pediatr Allergy Immunol. 2020;31(8):889-912. [PubMed]  [PMC]
  38. van Schoor NM, Lips P. Worldwide vitamin D status. Best Pract Res Clin Endocrinol Metab. 2011;25(4):671-680. [Crossref]  [PubMed]
  39. Institute of Medicine (US) Committee to Review Dietary Reference Intakes for Vitamin D and Calcium, Ross AC, Taylor CL, Yaktine AL, Del Valle HB, eds. Dietary Reference Intakes for Calcium and Vitamin D. Washington (DC): National Academies Press (US); 2011. [Link]
  40. Alexander EK, Pearce EN, Brent GA, et al. 2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum. Thyroid. 2017;27(3):315-389. [Crossref]  [PubMed]
  41. Kerver JM, Pearce EN, Ma T, Gentchev M, Elliott MR, Paneth N. Prevalence of inadequate and excessive iodine intake in a US pregnancy cohort. Am J Obstet Gynecol. 2021;224(1):82.e1-82.e8. [Crossref]  [PubMed]  [PMC]
  42. Derbyshire E, Obeid R. Choline, Neurological Development and Brain Function: A Systematic Review Focusing on the First 1000 Days. Nutrients. 2020;12(6):1731. Published 2020 Jun 10. [Crossref]  [PubMed]  [PMC]
  43. Obeid R, Derbyshire E, Schön C. Association between Maternal Choline, Fetal Brain Development, and Child Neurocognition: Systematic Review and Meta-Analysis of Human Studies. Adv Nutr. 2022;13(6):2445-2457. [Crossref]  [PubMed]  [PMC]
  44. Wallace TC, Fulgoni VL. Usual Choline Intakes Are Associated with Egg and Protein Food Consumption in the United States. Nutrients. 2017;9(8):839. Published 2017 Aug 5. [Crossref]  [PubMed]  [PMC]
  45. Hennigar SR, Lieberman HR, Fulgoni VL 3rd, McClung JP. Serum Zinc Concentrations in the US Population Are Related to Sex, Age, and Time of Blood Draw but Not Dietary or Supplemental Zinc. J Nutr. 2018;148(8):1341-1351. [Crossref]  [PubMed]
  46. Foster M, Herulah UN, Prasad A, Petocz P, Samman S. Zinc Status of Vegetarians during Pregnancy: A Systematic Review of Observational Studies and Meta-Analysis of Zinc Intake. Nutrients. 2015;7(6):4512-4525. Published 2015 Jun 5. [Crossref]  [PubMed]  [PMC]
  47. Rogne T, Tielemans MJ, Chong MF, et al. Associations of Maternal Vitamin B12 Concentration in Pregnancy With the Risks of Preterm Birth and Low Birth Weight: A Systematic Review and Meta-Analysis of Individual Participant Data. Am J Epidemiol. 2017;185(3):212-223. [Crossref]  [PubMed]  [PMC]
  48. Bath SC, Steer CD, Golding J, Emmett P, Rayman MP. Effect of inadequate iodine status in UK pregnant women on cognitive outcomes in their children: results from the Avon Longitudinal Study of Parents and Children (ALSPAC). Lancet. 2013;382(9889):331-337. [Crossref]  [PubMed]
  49. Piccoli GB, Clari R, Vigotti FN, et al. Vegan-vegetarian diets in pregnancy: danger or panacea? A systematic narrative review. BJOG. 2015;122(5):623-633. [Crossref]  [PubMed]
  50. Bastos Maia S, Rolland Souza AS, Costa Caminha MF, et al. Vitamin A and Pregnancy: A Narrative Review. Nutrients. 2019;11(3):681. Published 2019 Mar 22. [Crossref]  [PubMed]  [PMC]
  51. Checkley W, West KP Jr, Wise RA, et al. Maternal vitamin A supplementation and lung function in offspring. N Engl J Med. 2010;362(19):1784-1794. [Crossref]  [PubMed]
  52. Rothman KJ, Moore LL, Singer MR, Nguyen US, Mannino S, Milunsky A. Teratogenicity of high vitamin A intake. N Engl J Med. 1995;333(21):1369-1373. [Crossref]  [PubMed]
  53. Hartmann S, Brørs O, Bock J, et al. Exposure to retinoic acids in non-pregnant women following high vitamin A intake with a liver meal. Int J Vitam Nutr Res. 2005;75(3):187-194. [Crossref]  [PubMed]
  54. Connelly KJ, Boston BA, Pearce EN, et al. Congenital hypothyroidism caused by excess prenatal maternal iodine ingestion. J Pediatr. 2012;161(4):760-762. [Crossref]  [PubMed]  [PMC]
  55. Nishiyama S, Mikeda T, Okada T, Nakamura K, Kotani T, Hishinuma A. Transient hypothyroidism or persistent hyperthyrotropinemia in neonates born to mothers with excessive iodine intake. Thyroid. 2004;14(12):1077-1083. [PubMed]
  56. Rumbold A, Ota E, Hori H, Miyazaki C, Crowther CA. Vitamin E supplementation in pregnancy. Cochrane DatabaseSyst Rev. 2015;2015(9):CD004069. Published 2015 Sep 7. [Crossref]  [PubMed]  [PMC]
  57. Woods JR, Jr MA, Plessinger, and RK Miller, Vitamins C and E: missing links in preventing preterm premature rupture of membranes? Am J Obstet Gynecol, 2001;185(1):5-10. [Crossref]  [PubMed]
  58. Rumbold A, et al., Vitamin C supplementation in pregnancy. Cochrane Database Syst Rev, 2015; 2015(9): Cd004072. [Crossref]  [PubMed]  [PMC]
  59. Wang L, Wei L, Wang Z, Ren X, Yang F, Sun L. A meta-analysis of the effects of vitamin C supplementation for pregnant smokers on the pulmonary function of their offspring. BMC Pregnancy Childbirth. 2024;24(1):184. Published 2024 Mar 7. [Crossref]  [PubMed]  [PMC]
  60. McEvoy CT, Shorey-Kendrick LE, Milner K, et al. Effect of Vitamin C Supplementation for Pregnant Smokers on Offspring Airway Function and Wheeze at Age 5 Years: Follow-up of a Randomized Clinical Trial [published correction appears in JAMA Pediatr. 2023 Jan 1;177(1):104.]. [Crossref]  [PubMed]  [PMC]