Immunotherapy for Rare Solid Tumors and Sarcomas

İrfan KARAHANa , Seda KAHRAMANb , Bülent YALÇINb
aAnkara Bilkent City Hospital, Clinic of Medical Oncology, Ankara, Türkiye
bAnkara Yıldırım Beyazıt University Faculty of Medicine, Ankara Bilkent City Hospital, Department of Medical Oncology, Ankara, Türkiye

Karahan İ, Kahraman S, Yalçın B. Immunotherapy for rare solid tumors and sarcomas. In: Şendur MAN, ed. Current Immunotherapy Landscape for Solid Tumors. 1st ed. Ankara: Türkiye Klinikleri; 2024. p.130-5.

ABSTRACT
Management of rare tumors and sarcomas is a challenging issue due to their relatively low frequency and lack of adequate randomised trials, as well as their dismal prognosis. Over the past decade, research has focused on immunomodulatory strategies to enhance treatment responses. Immunomodulatory treatment can be classified as immune-checkpoint inhibitors, macrophage-based therapies, CART cell therapies and neoantigen-based therapies. In this section, these therapies, their results and future prospects will be discussed.

Keywords: Immunotherapy; rare tumors; sarcomas; immune check point inhibitors

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