CURRENT CONCEPTS IN RADIOTHERAPY FOR BENIGN DISORDERS

CurrentConceptsinRadiotherapyforBenignDisorders1-0-25kapak

Keloid and Hypertrophic Scars

Hakan GAMSIZa
aUniversity of Health Sciences Gülhane Faculty of Medicine, Department of Radiation Oncology, Ankara, Türkiye

Gamsız H. Keloid and hypertrophic scars. In: Uysal B, Gamsız H, eds. Current Concepts in Radiotherapy for Benign Disorders. 1st ed. Ankara: Türkiye Klinikleri; 2025. p.18-21.

ABSTRACT
Fibroproliferative benign diseases such as hypertrophic scars and keloids are caused by abnormal wound healing in susceptible individuals after burns, surgery, inflammation, or trauma. While the exact mechanism remains unclear, keloids exhibit distinct characteristics of fibroblasts compared to those in normal skin. Keloids can manifest months or years after skin damage and may continue to grow independently. They are more prevalent in individuals with a family history and are commonly observed in the 10-30 age group. Various treatment modalities are available, including intralesional steroid injections, surgical excision, cryotherapy, laser therapy, radiation therapy, and application of silicone gel sheets. Radiation therapy, particularly when combined with surgery within 24-48 hours, emerges as an effective and safe treatment approach. Electron therapy, superficial or orthovoltage X-rays, and brachytherapy represent viable RT options, each with distinct advantages and limitations. Using several fractions with higher doses per fraction is recommended in radiation therapy planning for optimal outcomes in keloid management.

Keywords: Keloid; cicatrix, hypertrophic; radiotherapy; brachytherapy

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