Kök Hücre

oral-biyokimya

Seval Türk, Deniz Yanık

Kök hücreler, rejenerasyon ve doku onarım potansiyeline sahip özel hücrelerdir. Vücutta birçok farklı dokunun oluşturulmasında kritik bir role sahip olup hem embriyonik hem de erişkin dokulardan izole edilebilirler. Bu bölüm; kök hücrelerin kaynaklarına, türlerine, farklılaşma özelliklerine ve farklılaşmadaki sinyal yolakları ile moleküler değişikliklere odaklanmaktadır. Ayrıca diş hekimliğinde kök hücre kavramını ve çeşitli dental kök hücre kaynaklarını ele almaktadır. Özellikle diş hekimliği alanında; dental pulpa, süt dişleri, dental folikül, apikal papilla, periodontal ligament, diş eti ve alveol kemiği gibi diş ve çevre dokuların kök hücreler açısından zengin kaynaklar olduğunu belirtmek esastır. Bu kök hücrelerin varlığı, dentinpulpa kompleksinin ve periodontal dokuların rejenerasyonu için klinik potansiyele sahiptir ve bir bütün olarak diş organın oluşumunu sağlayabilir. Kök Hücre bölümü, kök hücrelerin biyokimyası ve diş hekimliği bağlamında potansiyel uygulamaları için yol gösterici olacaktır.

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