Kutanöz Mastositoz

immunoloji alerji ozel 13-2 kapak

Merve ERKOÇa, Göksal KESKİNa
aAnkara Üniversitesi Tıp Fakültesi, İmmünoloji ve Alerji Hastalıkları BD, Ankara, TÜRKİYE

Erkoç M, Keskin G. Kutanöz mastositoz. Çildağ S, editör. İmmünolojik ve Alerjik Deri Hastalıkları. 1. Baskı. Ankara: Türkiye Klinikleri; 2020. p.25-8.

ÖZET
Mastositoz; bir veya daha fazla organda mast hücrelerinin anormal proliferasyonundan ve infiltrasyonundan kaynaklanan heterojen bir hastalık grubudur. Kutanöz mastositoz (CM) ciltle sınırlı mastositozdur. İzole kutanöz mastositoz baskın olarak çocukları etkilemekle birlikte nadiren de olsa yetişkin popülasyonu etkilemektedir. Kutanöz mastositoz 3 alt gruba ayrılmıştır ve en sık görülen şikayet kaşıntıdır. Kutanöz mastositoz tanısı tipik klinik bulguları olan hastalarda ciltten alınan biyopsiyledir. Tedavide amaç mast hücrelerden salgılanan mediyatörler ile ilişkili semptomların kontrolüdür. Kutanöz mastositoz prognozu hastanın başvuru sırasındaki yaş ile ilişkilidir.

Anahtar Kelimeler: Mastositoz, kutanöz; ürtikerya pigmentoza; mastositoma, deri

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