MICROBIAL MILESTONES: THE ROLE OF LACTATION ON INFANT MICROBIOTA
Buse Önen Ocak1
Buse Özer Bekmez2
1Ankara Bilkent City Hospital, Department of Neonatology, Ankara, Türkiye
2Ankara Bilkent City Hospital, Department of Neonatology, Ankara, Türkiye
Önen Ocak B, Özer Bekmez B. Microbial Milestones: The Role of Lactation on Infant Microbiota. Melek İM, Aydoğan S, eds. Microbiota. 1st ed. Ankara: Türkiye Klinikleri; 2025. p.73-78.
ABSTRACT
Breast milk it is known that the optimal food for the infant’s nutrition and development, protects against diseases such as gastrointestinal and respiratory system infections, asthma, atopy, and obesity. It is recommended by WHO (World Health Organization) and AAP (American Academy of Pediatrics) to continue breastfeeding along with complementary foods after exclusive breastfeeding for the first 6 months. Microbiota is the name given to the community of microorganisms that live in the human body. The most influential factor in the formation and development of microbiota is breastfeeding. The situation where a healthy microbial balance cannot be established is called dysbiosis, and its relationship with many diseases such as inflammatory bowel diseases, obesity, and diabetes has been demonstrated.Many factors affect the microbiota; birth method, antibiotic exposure, maternal nutrition, and maternal microbiota can be given as examples. The negative effects that all these factors can create can be reversed by breastfeeding. Breastmilk oligosaccharides (HMO) are very effective in the development of the microbiota. HMO is used by certain bacterial groups in the intestine, ensuring their relative abundance and also keeping the microbiome in balance by inhibiting the proliferation of certain pathogens. It has been observed that babies fed with breast milk have a microbiota rich in bifidobacteria.
Keywords: Breastmilk; Infant; Gut microbiata; Disbiozis
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Referanslar
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