Nervous System Diseases in Laboratory Animals: Traditional Review

veterinerbilichastaliklari10-3-24kapak

Yücel MERALa , Şamil Buğra KÖSEa
aOndokuz Mayıs University Faculty of Veterinary Medicine, Department of Internal Medicine, Samsun, Türkiye

ABSTRACT
Laboratory animals are animals that have been selected or modified for use in biomedical and medical research and can be housed in a laboratory environment. Many rodent species; mice, gerbils, hamsters, rabbits, ferrets, non-human primates are just some of the animals that can be considered as laboratory animals. Laboratory animals play a role in the diagnosis and treatment of diseases in humans and other animals, and in researching the effectiveness of pharmacological products and vaccines. Due to the widespread use of laboratory animals in scientific studies, the importance of the pathophysiology of natural and experimental infections in scientific studies, and the increasing use of some laboratory animals as pets, internal diseases of laboratory animals are becoming increasingly important. Although many factors such as some bacterial, viral, parasitic and fungal agents, traumas and congenital anomalies cause nervous system diseases, common neurological symptoms such as head tilt/ torticollis, seizures, paresis, nystagmus are observed that are not specific to a single agent. This is an indication of the importance of differential diagnosis in the diagnosis of nervous system diseases. In this review; some of the nervous system diseases seen in laboratory animals and neurologic findings of some diseases that are important in differential diagnosis are mentioned in the light of current knowledge.

Keywords: Laboratory animals; nervous system diseases; rodents; non-human primates; ferrets

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