PELVİK TABAN HASTALIKLARI VE OBSTRİKTİF DEFEKASYON SENDROMU

Dr. Öğr. Üyesi Miraç İlker PALA

Medipol Üniversitesi Tıp Fakültesi, Pendik Hastanesi, Genel Cerrahi AD, İstanbul, Türkiye

ÖZET

Pelvik taban hastalıkları ve obstrüktif defekasyon sendromu (ODS), gerek batılı ülkelerde gerekse Türkiye?de sık görülen rahatsızlıklardır. ODS, rektumun etkili ve hızlı bir şekilde boşaltılamadığı pelvik taban bozukluklarının bir alt tipidir. Kadınların %20’den fazlası hayatları boyunca en az bir pelvik taban hastalığı yaşamaktadır ve yaş, doğum sayısı ile obezite bu hastalıkların görülme sıklığını artıran faktörlerdir. Normal dışkılama süreci; rektumun dışkı ile dolması, rektoanal inhibitör refleksin (RAIR) aktivasyonu ve dışkılama sürecinin son evresinde levator ani kasının gevşemesiyle gerçekleşir. Bu fizyolojik sürecin herhangi bir aşamasındaki bozukluk, ODS’ye neden olabilir. Kabızlık etiyolojisi farklı nedenlere dayanmaktadır. Kolonik inertia (yavaş geçişli kons- tipasyon), konstipasyon predominant irritabl bağırsak sendromu (İBS) ve pelvik taban disfonksiyonu (ODS) yaygın sebeplerdir. ODS hastalarında genellikle aşırı ıkınma, tam boşaltamama ve perineye el ile destek olma gibi belirtiler görülmektedir. ODS tanısında ayrıntılı anamnez ve fizik muayene temel olmakla birlikte kolonik transit testi, defekografi ve anorektal manometri gibi testler kullanılmaktadır. Bu testler, fonksiyonel kabızlığın alt tiplerinin ayrımını yapmada ve pelvik taban fonksiyonlarını değerlendirmede kullanılır. ODS’nin tedavisi genellikle konservatif yöntemlerle başlar. Diyet değişiklikleri (lif ve sıvı tüketiminin artırılması), yaşam tarzı değişiklikleri ve pelvik taban fizyoterapisi, tedavi seçenekleri arasındadır. Pelvik taban fizyoterapisi ve biofeedback tedavisi, kas koordinasyonunu iyileştirerek semptomları azaltmada etkili olabilir. Ancak, her hastada yeterli yanıt alınamayabilir. Cerrahi seçenekler, konservatif yöntemlerin yetersiz kaldığı durumlarda düşünülmektedir. Laparoskopik ventral mesh rektopeksi (LVMR) gibi cerrahi işlemler, yapısal bozuklukları düzeltmek için tercih edilebilir, ancak bu yöntemlerin komplikasyon riskleri bulunmaktadır. Sonuç olarak, ODS ve pelvik taban hastalıkları, multifaktöryel rahatsızlıklar olup tanı ve tedavide hem konservatif hem de cerrahi yaklaşımlar gerektire- bilir. Hastalar, tedavi seçenekleri ve beklentiler konusunda ayrıntılı şekilde bilgilendirilmelidir.

Anahtar Kelimeler: Rektosel; Pelvik taban; Pelvik taban kusurları; Konstipasyon

Referanslar

  1. Jelovsek JE, Barber MD, Paraiso MF, et al. Functional bowel and anorectal disorders in patients with pelvic organ pro- lapse. Am J Obstet Gynecol. 2005;193(6):2105-11. [Crossref]  [PubMed]
  2. Meschia M, Buonaguidi A, Pifarotti P, et al. Prevalence of anal incontinence in women with symptoms of uri- nary incontinence and genital prolapse. Obstet Gyne- col. 2002;100(4):719-23. [Crossref]  [PubMed]
  3. Lewis SJ, Heaton KW. Stool form scale as a useful guide to intestinal transit time. Scand J Gastroenterol. 1997;32(9): 920-4. [Crossref]  [PubMed]
  4. Varma MG, Hart SL, Brown JS, et al. Obstructed defecation in middle aged women. Dig Dis Sci. 2008;53(10):2702-9. [Crossref]  [PubMed]  [PMC]
  5. Costilla VC, Foss-Orenstein AE. Constipation in adults: dagnosis and management. Curr Treat Options Gastroenterol. 2014;12(3):310-21. [Crossref]  [PubMed]
  6. Lalwani N, Moshiri M, Lee JH, et al. Magnetic resonance imaging of pelvic floor dysfunction. Radiol Clin North Am. 2013;51(6):1127-39. [Crossref]  [PubMed]
  7. Murad-Regades SM, Regadas Filho FS, Regadas FS, et al. Use of dynamic 3-dimensional transvaginal and tran- srectal ultrasonography to assess posterior pelvic floor dysfunction related to obstructed defecation. Dis Colon Rectum. 2014;57(2):228-36. [Crossref]  [PubMed]
  8. Khatri G. Magnetic resonance imaging of pelvic floor disorders. Top Magn Reson Imaging. 2014;23(4):259-73. [Crossref]  [PubMed]
  9. Chiaroni G, Kim SM, Vantini, Whitehead WE. Validation of the balloon evacuation test: reproducibility and agreement with findings from anorectal manometry and electromyog- raphy. Clin Gastroenterol Hepatol. 2014;12(12):2049-54. [Crossref]  [PubMed]
  10. Pucciani F, Ringressi MN. Obstructed defecation: the role of anorectal manometry. Tech Coloproctol. 2012;16(1):67-72. [Crossref]  [PubMed]
  11. Van Koughnett JA, da Silva G. Anorectal physiology and testing. Gastroenterol Clin North Am. 2013;42(4):713-28. [Crossref]  [PubMed]
  12. Podzemny V, Pescatori LC, Pescatori M. Management of obstructed defecation. World J Gastroenterol. 2015;21(4): 1053-60. [Crossref]  [PubMed]  [PMC]
  13. Starr JA, Drobnis EZ, Lenger S, et al. Outcomes of a compre- hensive nonsurgical approach to pelvic floor rehabilitation for urinary symptoms, defecatory dysfunction and pelvic pain. Female Pelvic Med Reconstr Surg. 2013;19(5):260-5. [Crossref]  [PubMed]
  14. Suares NC, Ford AC. Systematic review: the effects of fibre in the management of chronic idiopathic constipation. Aliment Pharmacol Ther. 2011;33:895-901. [Crossref]  [PubMed]
  15. Pucciani F, Raggioli M, Rigressi MN. Usefulness of psyllium in rehabilitation of obstructed defecation. Tech Coloproctol. 2011;15(4):377-83. [Crossref]  [PubMed]
  16. Bharucha AE. Difficult defecation: difficult problem assessment and management: what really helps? Gastroenterol Clin North Am. 2011;40(4):833-44. [Crossref]  [PubMed]
  17. Tarrerias AL, Abramowitz L, Marty MM, et al. Efficacy of a CO2-releasing suppository in dyschezia: a double-blind, randomized, placebo-controlled clinical trial. Dig Liver Dis. 2014;46(8):682-7. [Crossref]  [PubMed]
  18. Cotelle O, Cargill G, Marty MM, et al. A concomitant treatment by CO2-releasing suppositories improves the results of anorectal biofeedback training in patients with dyschezia: results of a randomized, double-blind, placebo-controlled trial. Dis Colon Rectum. 2014;57(6):781-9. [Crossref]  [PubMed]
  19. De Schryver AM, Keulmans YC, Peters HP, et al. Effects of regular physical activity on defecation pattern in middle aged patients complaining of chronic constipa- tion. Scand J Gastroenterol. 2005;40:422-9. [Crossref]  [PubMed]
  20. Chiarioni G, Whitehead WE, Pezza V, et al. Biofeedback is superior to laxatives for normal transit constipation due to pelvic floor dyssynergia. Gastroenterology. 2006;130(3):657-64. [Crossref]  [PubMed]
  21. Rao SS, Valestin J, Brown CK, et al. Long-term efficacy of biofeedback therapy for dyssynergic defecation: randomized controlled trial. Am J Gastroenterol. 2010;105(4):890-6. [Crossref]  [PubMed]  [PMC]
  22. Woodward S, Norton C, Chiarelli P. Biofeedback for treatment of chronic idiopathic constipation in adults. Cochrane Database Syst Rev. 2014;3:CD008486. [Crossref]  [PubMed]  [PMC]
  23. Dvorkin LS, Gladman MA, Epstein J, et al. Rectal intussusception in symptomatic patients is different from that in asymptomatic volunteers. Br J Surg. 2005;92:866-72. [Crossref]  [PubMed]
  24. Gouriou C, Chambaz M, Ropert A, et al. Management of solitary rectal ulcer syndome: Results of a french national survey: Société Nationale Française de Coloproctologie SN- FCP, France. Dig Liver Dis. 2020 Aug;52(8):885-888. Epub 2020 Jun 10. [Crossref]  [PubMed]
  25. Polin MR, Gleason JL, Szychowski JM, et al. Effects of transvaginal repair of symptomatic rectocele on symptom specific distress and impact on quality of life. Int J Gynae- col Obstet. 2012;117(3):224-7. [Crossref]  [PubMed]
  26. Pilzek AL, Raker CA, Sung VW. Are patients personal goals achieved after pelvic reconstructive surgery? Int Urogynecol J. 2014;25(3):347-50. [Crossref]  [PubMed]  [PMC]
  27. Sokol A.I., Walters M.D. Vaginal Enterocele Repair. In: Davila G.W., Ghoniem G.M., Wexner S.D. (eds) Pelvic Floor Dysfunction. Springer, London. 2008. [Crossref]
  28. Tsunoda A. Surgical Treatment of Rectal Prolapse in the Laparoscopic Era; A Review of the Literature. J Anus Rectum Colon. 2020 Jul 30;4(3):89-99. [Crossref]  [PubMed]  [PMC]
  29. Gosselink MP, Adusumilli S, Gorissen KJ, et al. Laparoscopic ventral rectopexy for fecal incontinence associated with high-grade internal rectal prolapse. Dis Colon Rectum. 2013;56:1409-14. [Crossref]  [PubMed]
  30. Tsunoda A, Ohta T, Kiyasu Y, et al. Laparoscopic ventral rectopexy for rectoanal intussusception: postoperative evaluation with proctography. Dis Colon Rectum. 2015;58(4):449-56. [Crossref]  [PubMed]
  31. Franceschilli L, Varvaras D, Capuano I, et al. Laparoscopic ventral rectopexy using biologic mesh for the treatment of obstructed defecation syndrome and/or fecal incontinence in patients with internal rectal prolapse: a critical appraisal of the first 100 cases. Tech Coloproctol. 2015;19(4):209-19. [Crossref]  [PubMed]
  32. Ahmad NZ, Stefan S, Adukia V, et al. Laparoscopic Ventral Mesh Rectopexy: Functional Outcomes after Surgery. Surg J (N Y). 2018;4(4):e205-e211. Published 2018 Oct 29. [Crossref]  [PubMed]  [PMC]
  33. Ommer A, Albrecht K, Wenger F, et al. Stapled transanal rectal resection (STARR): a new option in the treatment of obstructive defecation syndrome. Langenbecks Arch Surg. 2006;391:32-7. [Crossref]  [PubMed]
  34. Boccasanta P, Venturi M, Stuto A, et al. Stapled transanal rectal resection for outlet obstruction: a prospective multicenter trial. Dis Colon Rectum. 2004;47:1285-97. [Crossref]  [PubMed]
  35. Lehur PA, Stuto A, Fantoli M, et al. Outcomes of stapled transanal rectal resection vs. biofeedback for the treatment of outlet obstruction associated with rectal intussusception and rectocele: a multicenter, randomized, controlled trial. Dis Colon Rectum. 2008;51(11):1611-8. [Crossref]  [PubMed]
  36. Dodi G, Pietroletti R, Milito G, et al. Bleeding, incontinence, pain and constipation after STARR for obstructed defecation. Tech Coloproctol. 2003;7: 148-53. [Crossref]  [PubMed]
  37. Boenicke L, Jayne DG, Kim M, et al. What happens in stapled transanal rectum resection? Dis Colon Rectum. 2011;54(5):593-600. [Crossref]  [PubMed]
  38. Kohler K, Stelzner S, Helmichh G, et al. Results in the long term course after stapled transanal rectal resection (STARR). Langenbecks Arch Surg. 2012;397(5):771-8. [Crossref]  [PubMed]
  39. Glazener CM, Breeman S, Elders A, et al Mesh, graft, or standard repair for women having primary transvaginal anterior or posterior compartment prolapse surgery: two parallel-group, multicentre, randomised, controlled trials (PROS- PECT). Lancet. 2017 Jan 28;389(10067):381-392. [Crossref]  [PubMed]
  40. Abed H, Rahn DD, Lowenstein L, et al. Incidence and management of graft erosion, wound granulation, and dyspareunia following vaginal prolapse repair with graft materials: a systematic review. Int Urogynecol J. 2011 Jul;22(7):789-98. [Crossref]  [PubMed]
  41. Sung VW, Rardin CR, Raker CA, et al. Porcine subintestinal submucosal graft augmentation for rectocele repair: a randomized controlled trial. Obstet Gynecol. 2012 Jan;119(1):125-33. [Crossref]  [PubMed]  [PMC]
  42. Jia X, Glazener C, Mowatt G, et al. Efficacy and safety of using mesh or grafts in surgery for anterior and/or posterior vaginal wall prolapse: systematic review and meta-analysis. BJOG. 2008 Oct;115(11):1350-61. [Crossref]  [PubMed]
  43. Shao Y, Fu YX, Wang QF, et al. Khubchandani's procedure combined with stapled posterior rectal wall resection for rectocele. World J Gastroenterol. 2019 Mar 21;25(11):1421- 1431. [Crossref]  [PubMed]  [PMC]
  44. Isbert C, Germer CT. Transanale Verfahren bei funktionellen Darmerkrankungen [Transanal procedure for functional bowel diseases]. Chirurg. 2013 Jan;84(1):30-4, 36-8. German. [Crossref]  [PubMed]
  45. Simón MA, Bueno AM, Otero P, et al. A Randomized Controlled Trial on the Effects of Electromyographic Biofeedback on Quality of Life and Bowel Symptoms in Elderly Women With Dyssynergic Defecation. Int J Environ Res Public Health. 2019 Sep 4;16(18):3247. [Crossref]  [PubMed]  [PMC]
  46. Kaplan JA, Simianu VV. Pelvic Floor Nonrelaxation: Approach to Evaluation and Treatment. Clin Colon Rectal Surg. 2021 Jan;34(1):49-55. Epub 2020 Sep 4. [Crossref]  [PubMed]  [PMC]
  47. Madbouly KM, Hussein AM. Temporary sacral nerve stimulation in patients with fecal incontinence owing to rectal hyposensitivity: a prospective, double-blind study. Surgery. 2015 Jan;157(1):56-63. [Crossref]  [PubMed]
  48. Knowles CH, Thin N, Gill K, et al. Prospective randomized doubleblind study of temporary sacral nerve stimulation in patients with rectal evacuatory dysfunction and rectal hyposensitivity. Ann Surg 2012;255(04):643-649. [Crossref]  [PubMed]
  49. Payne I, Grimm LM Jr. Functional Disorders of Constipation: Paradoxical Puborectalis Contraction and Increased Perineal Descent. Clin Colon Rectal Surg. 2017 Feb;30(1):22-29. [Crossref]  [PubMed]  [PMC]