Pharmacotherapy of Musculoskeletal Conditions in the Elderly

Yeşim GÖKÇE KUTSALa , Tolga Reşat AYDOSb

aHacettepe University Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Ankara, Türkiye
bBaşkent University Faculty of Medicine, Department of Medical Pharmacology, Ankara, Türkiye

ABSTRACT
Musculoskeletal diseases negatively affect the quality of life of elderly individuals,and well-being in aging societies and continues to pose problems not only in medical, but also in social and economic terms as well. Physicians should be more alert during a prescription to older patients, consider the pharmacokinetic and pharmacodynamic changes associated with aging and monitor their health status with individual attention. The use of drugs for the musculoskeletal system, such as paracetamol, opioids, tramadol, duloxetine, drugs use in neuropathic pain, myorelaxans, drugs use in osteoporosis, nonsteroidal anti-inflammatory drugs, glucocorticoids and disease-modifying antirheumatic drugs requires an individual-based treatment protocol. Patients should be carefully evaluated for comorbidities, polypharmacy and major organ functionality before starting the medication and it is necessary to closely monitor adverse effects during the treatment.
Keywords: Musculoskeletal diseases; drug therapy; elderly

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