Physiopathology of Inflammation

biyomedikalozel5-1-24kapak

Şevket RUACANa
aHacettepe University Faculty of Medicine, Department of Medical Pathology Retired Faculy Member, Ankara, Türkiye

Ruacan Ş. Physiopathology of inflammation. In: Koçdor H, Pabuççuoğlu A, Zihnioğlu F, eds. Inflammation and in vitro Diagnostics. 1st ed. Ankara: Türkiye Klinikleri; 2024. p.1-5.

Article Language: EN

ABSTRACT
Inflammation is the collection of cellular and molecular mechanisms which enables organisms to defend themselves against injurious agents, environmental changes and other organisms. All living creatures have mechanisms of inflammation. The primary target of inflammation is to fight injurious stimuli, restore physiologic systems and repair the damages. Throughout the ages inflammation have been studied by Hippocrates, Galen, Celsus and Virchow. In the 19th century Ehrlich and Metchnikoff have described cells responsible for inflammatory responses. Today the principal mechanisms of inflammation with cellular and vascular reactions have been elucidated. New techniques in imaging, ability to measure minute quantities of biological substances, and sophisticated molecular genetic methods have resulted in a much better understanding of inflammation and perhaps means to modulate it to cure diseases.

Keywords: Inflammation; immunity; leukocytes

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