MICROBIOTA

microbiotakapak

PREGNANCY AND MICROBIOTA

Eda Tüfekçioğlu

Ankara Etlik City Hospital, Department of Neonatology, Ankara, Türkiye

Tüfekçioğlu E. Pregnancy and Microbiota. Melek İM, Aydoğan S, eds. Microbiota. 1st ed. Ankara: Türkiye Klinikleri; 2025. p.23-28.

ABSTRACT

Pregnancy is a very special process of life and has very wide effects on mother and baby development. Microbiota is a community of microorganisms that affects the entire body. Although the main microbiota component is the intestine, vaginal and endometrial microbiota are also very important during pregnancy. The microbiota composition of the body changes throughout the trimesters during pregnancy. These changes are related to the normal physiological process of pregnancy as well as to the dysbiosis that may occur. Dysbiosis in the endometrial, vaginal and gut microbiota during pregnancy can lead to some negative clinical outcomes in the mother and fetus. Dysbiosis during pregnancy is affected by the mother’s age, standard of living, infections she has had, her diet and the treatments she uses. As a result of dysbiosis during pregnancy, the risk of maternal complications such as preeclampsia, gestational diabetes melitus, infertility and recurrent miscarriages may increase in the mother. On the other hand, premature birth in the fetus and negative outcomes in microbiota development during postnatal infancy may be encountered. To prevent this dysbiosis, the use of pre-probiotics during pregnancy is a current issue and studies are needed.

Keywords: Pregnancy; Microbiota; Vagina; Endometrium; Intestine; Neonatal outcomes; Pregnancy complications

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