Proximal Optimization Technique and Tips in Bifurcation Interventions
Dr. Mehmet Taha Özkan
Gümüşhane State Hospital, Department of Cardiology, Gümüşhane, Türkiye
ABSTRACT
Bifurcation lesions represent a complex subset of coronary artery disease, accounting for approximately 15- 20% of percutaneous coronary interventions (PCI). These lesions carry a high risk of restenosis, thrombosis, and procedural complications. The Proximal Optimization Technique (POT) is a critical method designed to optimize stent expansion, particularly in the proximal main vessel (pMV), using balloons sized to the pMV diameter inflated at high pressures to enhance stent apposition.
This article details the technical steps of POT, emphasizing the significance of proper equipment selection and precise balloon positioning. The clinical outcomes, management of complications, and the efficacy of POT are also discussed. Data from clinical studies indicate that POT effectively reduces restenosis and stent thrombosis rates. Advanced imaging techniques (IVUS, OCT) and supplementary optimization strategies are recommended to manage potential complications and improve procedural success.
In conclusion, the accurate application of POT in bifurcation PCI is pivotal for improving both short- and long- term clinical outcomes. This technique has become an indispensable tool in interventional cardiology, partic- ularly for managing the complexities of bifurcation lesions.
Keywords: Percutaneous coronary intervention; Cardiology; Coronary Angiography; Proximal Optimization Technique
Citation
Referanslar
- Kukreja N, Serruys PW, De Bruyne B, Colombo A, Macaya C, Richardt G, Fajadet J, Hamm C, Goedhart D and Macours NJH. Sirolimus-eluting stents, bare metal stents or coronary artery bypass grafting for patients with multivessel disease including involvement of the proximal left anterior descend- ing artery: analysis of the Arterial Revascularization Thera- pies study part 2 (ARTS-II). 2009;95:1061-1066. [Crossref] [PubMed]
- Maznyczka A, Arunothayaraj S, Egred M, Banning A, Brunel P, Ferenc M, Hovasse T, Wlodarczak A, Pan M, Schmitz TJC and Interventions C. Bifurcation left main stenting with or without intracoronary imaging: Outcomes from the EBC MAIN trial. 2023;102:415-429. [Crossref] [PubMed]
- Hildick-Smith D, Behan MW, Lassen JF, Chieffo A, Lefèvre T, Stankovic G, Burzotta F, Pan M, Ferenc M and Bennett LJCCI. The EBC TWO Study (European Bifurcation Cor- onary TWO) A Randomized Comparison of Provisional T-Stenting Versus a Systematic 2 Stent Culotte Strategy in Large Caliber True Bifurcations. 2016;9:e003643. [Crossref] [PubMed]
- Yang JH, Lee JM, Park TK, Song YB, Hahn J-Y, Choi J-H, Choi S-H, Yu CW, Chun WJ and Oh JHJKCJ. The proximaloptimization technique improves clinical outcomes when treated without kissing ballooning in patients with a bifur- cation lesion. 2019;49:485-494. [Crossref] [PubMed] [PMC]
- Chevalier B, Mamas M, Hovasse T, Rashid M, Gómez-Hos- pital J, Pan M, Witkowski A, Crowley J, Aminian A and McDonald JJE. Clinical outcomes of the proximal optimi- sation technique (POT) in bifurcation stenting: Impact of proximal optimisation technique. 2021;17:e910. [Crossref] [PubMed] [PMC]
- Hakim D, Chatterjee A, Alli O, Turner J, Sattar A, Foin N and Leesar MAJCCI. Role of proximal optimization tech- nique guided by intravascular ultrasound on stent expansion, stent symmetry index, and side-branch hemodynamics in patients with coronary bifurcation lesions. 2017;10:e005535. [Crossref] [PubMed]
- Watanabe Y, Murasato Y, Yamawaki M, Kinoshita Y, Oku- bo M, Yumoto K, Masuda N, Otake H, Aoki J and Naka- zawa GJE. Proximal optimisation technique versus final kissing balloon inflation in coronary bifurcation lesions: the randomised, multicentre PROPOT trial: Randomised com- parison between POT and KBT. 2021;17:747. [Crossref] [PubMed] [PMC]