Dermatologic Emergencies

dermatology-emergencieskapak-1-0-25

Psoriasis-Erythema Nodosum

Bensu BULUT
Yenimahalle Training and Research Hospital, Clinic of Emergency Medicine, Ankara, Türkiye

Medine AKKAN ÖZ
Ankara Provincial Health Directorate, Ankara, Türkiye

Bulut B, Akkan Öz M. Psoriasis-erythema nodosum. In: Oğuztürk H, Görmeli Kurt N, eds. Dermatologic Emergencies. 1st ed. Ankara: Türkiye Klinikleri; 2025. p.157-63.

ABSTRACT

Psoriasis is a common skin disease that can present with different clinical findings and has chronic inflammation in its pathology. It may be associated with various comorbidities and may involve more than one system. Comorbidities that may be related with psoriasis include obesity, arthritis, cancer, autoimmune disease, chronic kidney disease, heart rhythm disorder, chronic obstructive pulmonary disease, fatty liver disease, Parkinsonism, various vascular involvement and psychiatric diseases. Psoriasis has a multifactorial pathogenesis in which genetic, environmental and behavioral factors may be effective. Chronic plaque psoriasis is frequemtly occurring form of psoriasis and is presented by sharpy outlined, erythematous, and hard-scaled plaques. Other important subtypes of psoriasis are guttate psoriasis, pustular psoriasis and erythrodermic psoriasis. In most patients, physical examination is the most important part of diagnosis. A definitive treatment for psoriasis has not been found, but multiple therapeutic approaches can improve the signs and symptoms of the disease. Phytotherapy, topical and systemic treatment are the main treatment options. Erythema nodosum (EN) is a relatively uncommon condition marked by red and tender subcutaneous nodules, generally on the anterior part of the legs, as a result of a delayed hypersensitivity reaction. Clinically, it is the most common form of panniculitis. Although EN can be idiopathic or secondary, it is most commonly idiopathic. The most common causes of EN include infections, use of drugs such as oral contraceptives and penicillin, pregnancy, inflammatory conditions such as sarcoidosis, Behçet’s disease, cancer and gastrointestinal diseases. The diagnosis of EN is often depends on history and physical examination findings of patient. EN is a condition that often resolves on its own and does not require treatment, especially in mild cases, usually resolving within a few weeks. Symptomatic treatment options include potassium iodide, nonsteroidal anti-inflammatory drugs (NSAII), intralesional or systemic corticosteroids.

Keywords: Psoriasis; erythema nodosum; panniculitis; plaque; nodule; arthritis; erythema; inflammatory skin disease

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