Dermatologic Emergencies

dermatology-emergencieskapak-1-0-25

Staphylococcal Scalded Skin Syndrome

Songül DOĞAN ARAÇ
University of Health Sciences Faculty of Medicine, Gazi Yaşargil Training and Research Hospital, Department of Emergency Medicine, Diyarbakır, Türkiye

Remzi ÇETİNKAYA
University of Health Sciences Faculty of Medicine, Gazi Yaşargil Training and Research Hospital, Department of Emergency Medicine, Diyarbakır, Türkiye

Doğan Araç S, Çetinkaya R. Staphylococcal scalded skin syndrome. In: Oğuztürk H, Görmeli Kurt N, eds. Dermatologic Emergencies. 1st ed. Ankara: Türkiye Klinikleri; 2025. p.75-9.

ABSTRACT

Staphylococcal Scalded Skin Syndrome (SSSS) is a disease caused by exotoxin-producing strains of Staphylococcus species, characterized by peeling of the skin. Although it is rarely seen in children over the age of six, it typically occurs within the first 48 hours of life. Additionally, it can also be seen in immunocompromised adults or patients with severe renal failure. The pathogenesis of the dis- ease is based on the cleavage of the desmoglein-1 protein by exotoxins, leading to intraepidermal desquamation. SSSS presents with widespread rashes and severe clinical symptoms due to the systemic spread of toxins.

Keywords: Erythema; blister; staphylococcal skin infections; infant, newborn, diseases

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