Treatment Modalities and Planning of Molar Incisor Hypomineralization-Affected Teeth

Erenay ALPAYÇETİNa , Yelda KASIMOĞLUa
aİstanbul University Faculty of Dentistry, Department of Pediatric Dentistry, İstanbul, Türkiye

Alpayçetin E, Kasımoğlu Y. Treatment modalities and planning of molar incisor hypomineralization-affected teeth. In: Şen Tunç E, ed. Molar Incisor Hypomineralization. 1st ed. Ankara: Türkiye Klinikleri; 2025. p.39-45.

ABSTRACT
Molar incisor hypomineralization (MIH) is becoming increasingly significant in dental practice. It is defined as a systemic hypomineralization affecting one to four permanent first molars, often alongside impacted incisors. Early diagnosis is crucial because MIH-affected teeth are more susceptible to caries and enamel loss after eruption. Various treatment options exist for MIH-affected molars and incisors, including preventive measures, restorations, extractions, and potential post-extraction orthodontics treatment. However, selecting the appropriate treatment can be complex, leading to challenges for dentists. This study aims to offer a comprehensive overview of the management strategies for MIH-affected teeth.

Keywords: Dental enamel hypoplasia; therapy

Referanslar

  1. Lygidakis NA, Wong F, Jalevik B, Vierrou AM, Alaluusua S, Espelid I. Best clinical practice guidance for clinicians dealing with children presenting with molar-incisor-Hypomineralisation (MIH): an EAPD policy document. Eur Arch Paediatr Dent. 2010;11(2):75-81. [Crossref]  [PubMed]
  2. Bekes K, Krämer N, van Waes H, Steffen R. The Wuerzburg MIH concept: part 2. The treatment plan. Oralprophylaxe & Kinderzahnheilkunde. 2016;38(4):171-5. [Crossref]
  3. Oreano MD, Santos PS, Borgatto AF, Bolan M, Cardoso M. Association between dental caries and molar-incisor hypomineralisation in first permanent molars: a hierarchical model. Comm Dent Oral Epidemiol. 2023;51:436-42. [Crossref]  [PubMed]
  4. Lygidakis NA, Garot E, Somani C, Taylor GD, Rouas P, Wong FSL. Best clinical practice guidance for clinicians dealing with children presenting with molar-incisor-hypomineralisation (MIH): an updated European academy of paediatric dentistry policy document. Eur Arch Paediatr Dent. 2022;23:3-21. [Crossref]  [PubMed]  [PMC]
  5. Baroni C, Marchionni S. MIH supplementation strategies: prospective clinical and laboratory trial. J Dent Res. 2011;90:371-6. [Crossref]  [PubMed]
  6. Crombie FA, Cochrane NJ, Manton DJ, Palamara JE, Reynolds EC. Mineralisation of developmentally hypomineralised human enamel in vitro. Caries Res. 2013;47:259-63. [Crossref]  [PubMed]
  7. Bakkal M, Abbasoglu Z, Kargul B. The effect of casein phosphopeptide-amorphous calcium phosphate on molar-incisor hypomineralisation: a pilot study. Oral Health Prev Dent. 2017;15:163-7.
  8. William V, Messer LB, Burrow MF. Molar incisor hypomineralization: review and recommendations for clinical management. Pediatr Dent. 2006;28:224-32.
  9. Abbasi Z, Bahrololoom ME, Shariat MH, Bagheri R. Bioactive glasses in dentistry: a review. J Dent Biomater. 2015;2:1-9.
  10. Bekes K, Heinzelmann K, Lettner S, Schaller HG. Efficacy of desensitizing products containing 8% arginine and calcium carbonate for hypersensitivity relief in MIH-affected molars: an 8-week clinical study. Clin Oral Investig. 2017;21:2311-7. [Crossref]  [PubMed]  [PMC]
  11. Reynolds EC, Cai F, Cochrane NJ, Shen P, Walker GD, Morgan MV, Reynolds C. Fluoride an casein phosphopeptide-amorphous calcium phosphate. J Dent Res. 2008;87:344-8. [Crossref]  [PubMed]
  12. Crombie F, Manton D, Kilpatrick N. Aetiology of molar-incisor hypomineralization: a critical review. Int J Paediatr Dent. 2009;19:73-83. [Crossref]  [PubMed]
  13. Pasini M, Giuca MR, Scatena M, Gatto R, Caruso S. Molar incisor hypomineralization treatment with casein phosphopeptide and amorphous calcium phosphate in children. Minerva Stomatol. 2018;67:20-5. [Crossref]  [PubMed]
  14. Bekes K, Steffen R, & Krämer N. Update of the molar incisor hypomineralization: Würzburg concept. Eur Arch Paediatr Dent. 2023;24(6), 807-13. [Crossref]  [PubMed]  [PMC]
  15. Kim Y, Son HH, Yi K, Ahn JS, Chang J. Bleaching effects on color, chemical and mechanical properties of white spot lesions. Oper Dent. 2016;41(3):318-26. [Crossref]  [PubMed]
  16. Fayle SA. Molar incisor Hypomineralization: restorative management. Eur J Paediatr Dent. 2003;3:121-6.
  17. Crombie F, Manton D, Palamara J, Reynolds E. Resin infiltration of developmentally hypomineralised enamel. Int J Paedriatr Dent. 2014;24(1):51-5. [Crossref]  [PubMed]
  18. Paris S, Schwendicke F, Seddig S, Mueller WD, Dorfer C, Meyer-Lueckel H. Micro-hardness and mineral loss of enamel lesions after infiltration with various resins: influence of infiltrant composition and application frequency in vitro. J Dent. 2013;41(6):543-8. [Crossref]  [PubMed]
  19. Ceci M, Rattalino D, Viola M, Beltrami R, Chiesa M, Colombo M, Poggio C. Resin infiltrant for non-cavitated caries lesions: evaluation of color stability. J Clin Exp Dent. 2017;9(2):3231-e237. [Crossref]  [PubMed]  [PMC]
  20. Chałas R, Jurczykowska M, Marczyński R, Pels E. Composite inlays as a modern way of posterio restorations in the dental arch. Pol J Public Health. 2014;124(2):99-102. [Crossref]
  21. Koch MJ, Garcia-Godoy F. The clinical performance of laboratory-fabricated crowns placed on first permanent molars with developmental defects. J Am Dent Assoc. 2000;131(9):1285-90. [Crossref]  [PubMed]
  22. Sabandal MM, Schafer E. Amelogenesis imperfecta: review of diagnostic findings and treatment concepts. Odontol. 2016;104(3):245-56. [Crossref]  [PubMed]
  23. Scheibenbogen-Fuchsbrunner A, Manhart J, Kremers L, Kunzelmann KH, Hickel R. Two-year clinical evaluation of direct and indirect composite restorations in posterior teeth. J Prosthet Dent. 1999;82(4):391-7. [Crossref]  [PubMed]
  24. Eichenberger M, Erb J, Zwahlen M, et al. The timing of extraction of non-restorable first permanent molars: a systematic review. Eur J Paediatr Dent. 2015;16:272-8.
  25. Kirschneck C, Proff P. Age assessment in orthodontics and general dentistry. Quintessence Int. 2018;49(4):313-23.
  26. Cobourne MT, Williams A, Harrison M. National clinical guidelines for the extraction of first permanent molars in children. Br Dent J. 2014;217:643-8. [Crossref]  [PubMed]
  27. Bekes K. Molar Incisor Hypomineralization A Clinical Guide to Diagnosis and Treatment. Springer Nature Switzerland AG; 2020. p.190. [Crossref]
  28. Williams JK, Gowans AJ. Hypomineralised first permanent molars and the orthodontist. Eur J Paediatr Dent. 2003;4:129-32.
  29. Alqanas S, Alsahiem J, Aljami A, Alsudairi N, Ahmad S, Sharma S, et al. Factors related to spontaneous space closure following early first permanent molar extraction: A systematic review. Int J Paediatr Dent. 2024. [Crossref]  [PubMed]
  30. Williams JK, Gowans AJ. Hypomineralised first permanent molars and the orthodontist. Eur J Paediatr Dent. 2003;4:129-32.
  31. Linner T, Khazaei Y, Bucher K, Pfisterer J, Hickel R, Kuhnisch J. Comparison of four different treatment strategies in teeth with molar-incisor hypomineralization-related enamel breakdown-a retrospective cohort study. Int J Paediatr Dent. 2020;30:597-606. [Crossref]  [PubMed]
  32. Sonmez H, Saat S. A clinical evaluation of deproteinization and different cavity designs on resin restoration performance in MIH-affected molars: two-year results. J Clin Pediatr Dent. 2017;41:336-42. [Crossref]  [PubMed]
  33. Seifo N, Cassie H, Radford JR, Innes NPT. Silver diamine fluoride for managing carious lesions: an umbrella review. BMC Oral Health. 2019;19:145. [Crossref]  [PubMed]  [PMC]
  34. Ballikaya E, Unverdi GE, Cehreli ZC. Management of initial carious lesions of hypomineralized molars (MIH) with silver diamine fluoride or silver-modified atraumatic restorative treatment (SMART): 1-year results of a prospective, randomized clinical trial. Clin Oral Investig. 2022;26:2197-205. [Crossref]  [PubMed]  [PMC]
  35. Kotsanos N, Kaklamanos EG, Arapostathis K. Treatment management of first permanent molars in children with molar-incisor hypomineralisation. Eur J Paediatr Dent. 2005;6:179-84.
  36. Oh N, Nam S, Lee J, Kim H. Retrospective study on the survival rate of preformed metal crowns in permanent first molars. J Korean Acad Pediatr Dent. 2020;47:140-7. [Crossref]
  37. Talekar AL, Waggoner WF, Silotry TMH, Musale PK, Chaudhari GS. Prospective, randomized, clinical evaluation of preformed zirconia crowns and stainless steel crowns on permanent first molars: 12-month results. Pediatr Dent. 2023;45:232-9.
  38. Shayestehpour S, Sharma K, Mosor E, Omara M, Ritschl V, Shayestehpour S, Stamm T, Bekes K. Patient-reported outcome measures for pediatric dental patients: a methodological review and mapping exercise. J Evid Based Dent Pract. 2022;22: 101661. [Crossref]  [PubMed]
  39. Hasmun N, Vettore MV, Lawson JA, Elcock C, Zaitoun H, Rodd HD. Determinants of children's oral health-related quality of life following aesthetic treatment of enamel opacities. J Dent. 2020;98: 103372. [Crossref]  [PubMed]