INVASIVE INTERVENTIONS IN STRUCTURAL HEART DISEASES: COMPREHENSIVE TECHNIQUES

Invasive Interventions in Structural Heart Diseases-kapak

TRICVALVE-TRANSCATHETER BICAVAL VALVE SYSTEM

Duygu İnan

Başakşehir Çam and Sakura City Hospital, Department of Cardiology, İstanbul, Türkiye

İnan D. Tricvalve-Transcatheter Bicaval Valve System. In: Tanık VO, Özlek B, editors. Invasive Interventions in Structural Heart Diseases: Comprehensive Techniques. 1st ed. Ankara: Türkiye Klinikleri; 2025. p.551-562.

ABSTRACT

Severe tricuspid regurgitation (TR) remains an important clinical challenge, associated with high morbidity and mortality. Traditional surgical options, while effective, are often not feasible for patients with prohibitive surgical risks. In recent years, several transcatheter therapies have emerged, including edge-to-edge repair systems, annuloplasty devices, and orthotopic valve replacements, offering significant advances in the management of TR. Among these, the TricValveTranscatheter Bicaval Valve System stands out as a minimally invasive solution specifically designed for patients with severe symptomatic TR and caval reflux who are ineligible for surgery. By targeting the superior vena cava (SVC) and inferior vena cava (IVC), the TricValve system effectively alleviates symptoms and improves hemodynamic stability in selected high-risk patients. This chapter was explored the design, clinical context, procedural considerations and outcomes of the TricValve system and highlighted its role as an important addition to the growing transcatheter treatment initiatives for TR.

Keywords: Tricuspid valve regurgitation; Vena cava inferior; Vena cava superior; Venous valves

Referanslar

  1. Demir OM, Regazzoli D, Mangieri A, Ancona MB, Mitomo S, Weisz G, et al. Transcatheter Tricuspid Valve Replacement: Principles and Design. Front Cardiovasc Med. 2018;5:129. [Crossref]  [PubMed]  [PMC]
  2. d'Arcy JL, Coffey S, Loudon MA, Kennedy A, Pearson-Stuttard J, Birks J, et al. Large-scale community echocardiographic screening reveals a major burden of undiagnosed valvular heart disease in older people: the OxVALVE Population Cohort Study. Eur Heart J. 2016;37(47):3515-3522. [Crossref]  [PubMed]  [PMC]
  3. Fender EA, Zack CJ, Nishimura RA. Isolated tricuspid regurgitation: outcomes and therapeutic interventions. Heart. 2018;104(10):798-806. Epub 2017 Dec 11. [Crossref]  [PubMed]  [PMC]
  4. Wang N, Fulcher J, Abeysuriya N, McGrady M, Wilcox I, Celermajer D, Lal S. Tricuspid regurgitation is associated with increased mortality independent of pulmonary pressures and right heart failure: a systematic review and meta-analysis. Eur Heart J. 2019;40(5):476-484. [Crossref]  [PubMed]
  5. Zack CJ, Fender EA, Chandrashekar P, Reddy YNV, Bennett CE, Stulak JM, et al. National Trends and Outcomes in Isolated Tricuspid Valve Surgery. J Am Coll Cardiol. 2017 Dec 19;70(24):2953-2960. [Crossref]  [PubMed]
  6. Rodés-Cabau J, Hahn RT, Latib A, Laule M, Lauten A, Maisano F, et al. Transcatheter Therapies for Treating Tricuspid Regurgitation. J Am Coll Cardiol. 2016 Apr 19;67(15):1829-1845. [Crossref]  [PubMed]
  7. Figulla HR, Kiss K, Lauten A. Transcatheter interventions for tricuspid regurgitation - heterotopic technology: TricValve. EuroIntervention. 2016 Sep 18;12(Y):Y116-8. [Crossref]  [PubMed]
  8. Maisano F, Hahn R, Sorajja P, Praz F, Lurz P. Transcatheter treatment of the tricuspid valve: current status and perspectives. Eur Heart J. 2024 Mar 14;45(11):876-894. [Crossref]  [PubMed]
  9. Ro R, Tang GHL, Seetharam K, Khera S, Sharma SK, Kini AS, et al. Echocardiographic Imaging for Transcatheter Tricuspid Edge-to-Edge Repair. J Am Heart Assoc. 2020 Mar 3;9(5):e015682. [Crossref]  [PubMed]  [PMC]
  10. Hahn RT, Weckbach LT, Noack T, Hamid N, Kitamura M, Bae R, et al. Proposal for a Standard Echocardiographic Tricuspid Valve Nomenclature. JACC Cardiovasc Imaging. 2021 Jul;14(7):1299-1305. [Crossref]  [PubMed]
  11. Hahn RT. State-of-the-Art Review of Echocardiographic Imaging in the Evaluation and Treatment of Functional Tricuspid Regurgitation. Circ Cardiovasc Imaging. 2016 Dec;9(12):e005332. [Crossref]  [PubMed]
  12. Prihadi EA, Delgado V, Leon MB, Enriquez-Sarano M, Topilsky Y, Bax JJ, et al. Morphologic Types of Tricuspid Regurgitation: Characteristics and Prognostic Implications. JACC Cardiovasc Imaging. 2019 Mar;12(3):491-499. [Crossref]  [PubMed]
  13. Adler DS. Non-functional tricuspid valve disease. Ann Cardiothorac Surg. 2017 May;6(3):204-213. [Crossref]  [PubMed]  [PMC]
  14. Muraru D, Badano LP, Hahn RT, Lang RM, Delgado V, Wunderlich NC, et al. Atrial secondary tricuspid regurgitation: pathophysiology, definition, diagnosis, and treatment. Eur Heart J. 2024 Mar 14;45(11):895-911. [Crossref]  [PubMed]  [PMC]
  15. Dreyfus GD, Martin RP, Chan KM, Dulguerov F, Alexandrescu C. Functional tricuspid regurgitation: a need to revise our understanding. J Am Coll Cardiol. 2015 Jun 2;65(21):2331-6. [Crossref]  [PubMed]
  16. Kim JB, Spevack DM, Tunick PA, Bullinga JR, Kronzon I, Chinitz LA, et al. The effect of transvenous pacemaker and implantable cardioverter defibrillator lead placement on tricuspid valve function: an observational study. J Am Soc Echocardiogr. 2008 Mar;21(3):284-7. [Crossref]  [PubMed]
  17. Lauten A, Laube A, Schubert H, Bischoff S, Nietzsche S, Horstkötter K, et al. Transcatheter treatment of tricuspid regurgitation by caval valve implantation--experimental evaluation of decellularized tissue valves in central venous position. Catheter Cardiovasc Interv. 2015 Jan 1;85(1):150-60. [Crossref]  [PubMed]
  18. Lauten A, Dreger H, Schofer J, Grube E, Beckhoff F, Jakob P, et al. Caval Valve Implantation for Treatment of Severe Tricuspid Regurgitation. J Am Coll Cardiol. 2018 Mar 13;71(10):1183-1184. [Crossref]  [PubMed]
  19. Taramasso M, Hahn RT, Alessandrini H, Latib A, Attinger-Toller A, Braun D, et al. The International Multicenter TriValve Registry: Which Patients Are Undergoing Transcatheter Tricuspid Repair? JACC Cardiovasc Interv. 2017 Oct9;10(19):1982-1990. [Crossref]  [PubMed]
  20. Blasco-Turrión S, Briedis K, Estévez-Loureiro R, Sánchez-Recalde A, Cruz-González I, Pascual I, et al. Bicaval TricValve Implantation in Patients With Severe Symptomatic Tricuspid Regurgitation: 1-Year Follow-Up Outcomes. JACC Cardiovasc Interv. 2024 Jan 8;17(1):60-72. [Crossref]  [PubMed]
  21. Amat-Santos IJ, Estevez-Loureiro R, Sánchez-Recalde Á, Cruz-González I, Pascual I, Mascherbauer J, et al. EuroIntervention. 2023 Aug 7;19(5):e450-e452. [Crossref]  [PubMed]  [PMC]
  22. Abdul-Jawad Altisent O, Benetis R, Rumbinaite E, Mizarien V, Codina P, Gual-Capllonch F, et al. Caval Valve Implantation (CAVI): An Emerging Therapy for Treating Severe Tricuspid Regurgitation. J Clin Med. 2021 Oct 7;10(19):4601. [Crossref]  [PubMed]  [PMC]
  23. Lauten A, Dreger H, Laule M, Stangl K, Figulla HR. Caval Valve Implantation. Interv Cardiol Clin. 2018 Jan;7(1):57-63. Epub 2017 Oct 12. [Crossref]  [PubMed]
  24. Bertrand PB, Hung J. Bicaval Valve Implantation for Severe Tricuspid Regurgitation: Thinking Outside the Valve Box. JACC Case Rep. 2019 Dec 18;1(5):725-726. [Crossref]  [PubMed]  [PMC]
  25. Lauten A, Laube A, Schubert H, Bischoff S, Nietzsche S,Horstkötter K, et al. Transcatheter treatment of tricuspid regurgitation by caval valve implantation--experimental evaluation of decellularized tissue valves in central venous position. Catheter Cardiovasc Interv. 2015 Jan 1;85(1):150-60. Epub 2014 Feb 1. [Crossref]  [PubMed]